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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNND1
All Species:
21.82
Human Site:
Y221
Identified Species:
80
UniProt:
O60716
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60716
NP_001078927.1
968
108170
Y221
S
R
H
Y
E
D
G
Y
P
G
G
S
D
N
Y
Chimpanzee
Pan troglodytes
XP_001140660
968
108198
Y221
S
R
H
Y
E
D
G
Y
P
G
G
S
D
N
Y
Rhesus Macaque
Macaca mulatta
XP_001096747
968
108123
Y221
S
R
H
Y
E
D
G
Y
P
G
G
S
D
N
Y
Dog
Lupus familis
XP_849632
967
107998
Y221
S
R
H
Y
E
D
G
Y
P
G
S
S
D
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
P30999
938
104906
Y221
G
R
H
Y
E
D
G
Y
P
G
G
S
D
N
Y
Rat
Rattus norvegicus
NP_001101210
932
104053
Y221
G
R
H
Y
E
D
G
Y
P
G
G
S
D
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q8AXM9
859
94542
D211
G
R
I
Y
G
S
E
D
A
Y
G
L
E
D
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
97.9
N.A.
94.7
94.4
N.A.
N.A.
N.A.
48.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
100
98.9
N.A.
95.6
95.2
N.A.
N.A.
N.A.
62.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
86
0
15
0
0
0
0
86
15
15
% D
% Glu:
0
0
0
0
86
0
15
0
0
0
0
0
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
43
0
0
0
15
0
86
0
0
86
86
0
0
0
0
% G
% His:
0
0
86
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
0
% N
% Pro:
0
0
0
0
0
0
0
0
86
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
58
0
0
0
0
15
0
0
0
0
15
86
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
100
0
0
0
86
0
15
0
0
0
0
86
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _